Immunohistochemical demonstration of GABAergic neurons in the enteric nervous system

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Immunohistochemical demonstration of GABAergic neurons in the enteric nervous system.

Application of a highly specific antiserum against GABA to whole-mount preparations of the guinea pig and rat myenteric plexus resulted in discrete and unambiguous immunolabeling of a subpopulation of myenteric neuronal cell bodies and fibers. The anti-GABA antiserum, which was raised against GABA conjugated by glutaraldehyde to BSA, was applied to glutaraldehyde-fixed whole mounts and subseque...

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The enteric nervous system.

T HE enteric nervous system is a collection of neu-rons in the gastrointestinal tract 1 that constitutes the " brain of the gut " and can function independently of the central nervous system. 2 This system controls the motility, 3,4 exocrine and endocrine secretions, 5 and microcirculation 6 of the gastrointestinal tract; it is also involved in regulating immune and inflammatory processes. 7 In...

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ژورنال

عنوان ژورنال: The Journal of Neuroscience

سال: 1986

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.06-06-01628.1986